Extracting and analyzing relevant medical information from large-scale databases such as biobanks poses considerable challenges. To exploit such "big data," attempts have focused on large sampling ...

Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Feb. 21, 2026 Researchers have mapped the genetic risk of hemochromatosis across the UK and Ireland for the first time, uncovering striking hotspots in north-west Ireland and the Outer Hebrides. In ...