Cucumber is an economically important crop worldwide, ranking as the third most-produced vegetable after tomatoes and onions.

Structural genetic variants include large (>50 base pairs) duplications, inversion, translocations or deletions. Recent advances in long-read sequencing and optical genome mapping, combined with more ...

Research co-led by King's College London and Sidra Medicine, Qatar, has produced the most detailed map to date of large-scale genetic differences in the Qatari population, providing a clearer picture ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

A new genomic method has enabled multiple people with rare conditions to receive diagnoses that were previously unattainable by identifying complex structural genetic changes that are often missed by ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

SAVANA uses a machine learning algorithm to identify cancer-specific structural variations and copy number aberrations in long-read DNA sequencing data. The complex structure of cancer genomes means ...

This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. A closeup shot of a laboratory worker arranging pipette tips in a blue container for a ...

Recent advances in genome sequencing have improved all aspects of uncovering the human genome. One of the unlocked areas includes variant calling, or identifying and cataloging genetic variations, ...

Short-read sequencing has helped scientists identify and study genetic variants that increase Alzheimer’s disease risk, for example in the APOE, TREM2, and other genes. Yet these methods fail to ...