Researchers developed a humanized mouse model that better predicts how antibody drugs interact with the immune system. The ...

A new study from Cold Spring Harbor Laboratory Professor Nicholas Tonks, graduate student Yuxin Cen, and postdoctoral fellow ...

Alzheimer's disease is often measured in statistics: millions affected worldwide, cases rising sharply, costs climbing into the trillions. For families, the disease is experienced far more intimately.

The Tonks lab studied PTP1B inhibition in a mouse model of Alzheimer’s disease. When PTP1B was deleted, as shown in the ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital and Baylor College of Medicine recently made an important advance in neurodegenerative disease ...

Researchers have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification. This development marks a pivotal step forward in infectious disease ...

This year could mark a turning point for one of science’s most familiar animals: the laboratory mouse. For decades, mice and rats have been indispensable to biomedical research, underpinning ...