South Korean researchers have, for the first time in the world, uncovered how messenger ribonucleic acid (mRNA) vaccines enter human cells, function inside the body, and are blocked by certain ...
RNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production.
A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...
Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...
Pioneering clinical trial testing how personalised mRNA vaccines can enable the immune system to target recurring pancreatic ...
Since addressing the COVID-19 pandemic, mRNA vaccines have risen as a promising tool for treating a broad range of diseases, such as cancer and genetic disorders. To be effective, foreign mRNA in ...
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various ...
Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...
Researchers from the University of Cologne and the Max Planck Institute of Biochemistry show that the targeted interaction of two proteins ensures that a key control mechanism in the formation of ...
Researchers at MIT have unveiled a way to coax an aging immune system into acting young again, using the same kind of mRNA technology that powered the first COVID-19 vaccines. Instead of trying to ...
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