The intricate interplay between heparan sulfate and the extracellular matrix is fundamental to tissue development, repair and disease modulation. Heparan sulfate, a complex glycosaminoglycan attached ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

In cell and animal models of amyotrophic lateral sclerosis (ALS), the expression of toxic dipeptides in neurons led to changes in the extracellular matrix (ECM) as a protective response. The authors ...

This neon tapestry of red and blue is a unique look at the space between cells in the body known as the extracellular matrix. This image was created using a new labeling technique that allows ...

Extracellular vesicles (EVs), including exosomes, microvesicles, apoptotic bodies, and many other EV subtypes, have emerged as critical mediators of ...