Teplizumab has shown significant preservation of C-peptide levels in newly diagnosed type 1 diabetes (T1D) patients, indicating the potential for modifying disease progression. Combining teplizumab ...
The 6 CD3 adaptor molecules of the T-cell receptor (TCR) complex (CD3γ, CD3δ and two each of CD3ɛ and CD3ζ chains) contain a total of 10 immunoreceptor tyrosine-based activation motifs (ITAMs) in ...
Tiziana Life Sciences Ltd., which is developing the intranasal fully human anti-CD3 monoclonal antibody foralumab for neurological indications, has reported results from studies using a nasal anti-CD3 ...
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